Endocrine Abstracts

Interrelationships between HPA axis and sleep architecture are well documented and increased glucocorticoid levels seem associated with quantitative and qualitative sleep disruptions. The knowledge about sleep parameters in chronic hypercortisolism in humans is scanty. Our aim was to evaluate sleep efficiency in patients with Cushing’s syndrome (CS) at time of diagnosis, without ongoing specific therapy, using wrist actigraphy, a methodology that provides good estimations...